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"A landmark exploration of one of the most consequential and mysterious issues of our time: the rise of chronic illness and autoimmune diseases. A silent epidemic of chronic illnesses afflicts tens of millions of Americans: these are diseases that are poorly understood, frequently marginalized, and can go undiagnosed and unrecognized altogether. Renowned writer Meghan O'Rourke delivers a revelatory investigation into this elusive category of "invisible"...
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One day in 2009, twenty-four-year-old Susannah Cahalan woke up alone in a strange hospital room, strapped to her bed, under guard, and unable to move or speak. A wristband marked her as a "flight risk, " and her medical records--chronicling a monthlong hospital stay of which she had no memory at all--showed hallucinations, violence, and dangerous instability. Cahalan tells the astonishing true story of her inexplicable descent into madness and the...
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"Our bodies are protected by a complex defense system - an army that stands ready to combat dangerous invaders. But sometimes wires get crossed and our defenders turn against the body they are supposed to protect. Then we fall prey to autoimmune diseases such as rheumatoid arthritis, lupus, or type 1 diabetes. In all there are more than a hundred such diseases, which can ruin lives and sometimes end them prematurely. And these diseases are on the...
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This work takes readers on a global journey of discovery spanning 60 years, involving scores of scientists, and encompassing the history of transplants and immunology. That journey has revealed astonishing links between who we are as individuals and our never-ceasing struggle to survive disease. Most of the 25,000 genes we possess are the same for all of us. Compatibility genes are those that vary most from person to person and give each of us a unique...
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